The 2015 Conference of Chinese Society of Veterinary Science

Efficacy test of a Mycoplasma hyorhinis subunit vaccine in SPF pigs

CW Hsu, JS Wu, CY Wu, KM Huang, CS Chang, WZ Huang, JF Lai, HJ Lin, JP Wang, ZW Chen, JH Lin

Mycoplasma hyorhinis is a causative agent of swine polyserositis, pneumonia and arthritis. This pathogen can be isolated from the upper respiratory tract and tonsil of pigs. M. hyorhinis infection in pigs cause significant economic losses including growth retardation, poor food conversion rate and increased susceptibility to other swine pathogens. Vaccination is considered as one of the most effective strategies to control Mycoplasma infection. In this study, specific pathogen free (SPF) pigs were randomly assigned into vaccine and control groups. Gross and histopathological lesions, daily body weight gain and seroconversion were evaluated. It is indicated that pigs immunization M. hyorhinis subunit vaccine can provide a good protection to M. hyorhinis infection. These result suggest the subunit vaccine can be an effective tool to prevent M. hyorhinis infection in pigs.