In the course of vaccine development, challenge models are necessary to develop. PRRS is one of the diseases that presents its own issues in this area and we have developed a PRRS challenge model using a North American genotype, isolated locally, as a challenge strain. Using this model, blue ear is seen consistently in 30% of the pigs challenged.

The PRRS challenge model - pigs with "blue-ear"

APP (APXI and APXII)-sensitive TG mice were also developed as part of the vaccine testing needs.

APP (APXI and APXII)-sensitive mice