In vivo

In the course of vaccine development, challenge models are necessary to develop. PRRS is one of the diseases that presents its own issues in this area and we have developed a PRRS challenge model using a North American genotype, isolated locally, as a challenge strain. Using this model, blue ear is seen consistently in 30% of the pigs challenged.

The PRRS challenge model - pigs with "blue-ear"

APP (APXI and APXII)-sensitive TG mice were also developed as part of the vaccine testing needs.

APP (APXI and APXII)-sensitive mice