The 2016 Conference of Chinese Society of Veterinary Science

Field efficacy of a novel bivalent vaccine of Mycoplasma hyopneumoniae plus PCV2 in a Taiwan pig farm

MW Hsieh, CS Chang, WZ Huang, JP Wang, ZW Chen, JH Lin

Porcine circovirus type 2 (PCV2) and Mycoplasma hyopneumoniae are both important infectious pathogens of pig production worldwide. Many research evidences have shown that vaccination is effective to control both diseases. In the present study, a novel bivalent vaccine of M. hyopneumoniae plus PCV2 was developed. And a field trial is performed in a commercial pig farm. One hundred 3-week-old healthy pigs were randomly assigned into two groups (50 pigs/group). Blood samples were collected and to determine the anti-M. hyopneumoniae and anti-PCV2 IgG titers using ELISA. Level of PCV2 viremia was analyzed using real-time PCR. The results indicated that pigs immunized with this vaccine showed no adverse side effect and elicited good immune responses toward PCV2 and M. hyopneumoniae. Significantly lower PCV2 viremia and higher survival rate in vaccinated pigs were observed. This trial demonstrated this novel bivalent vaccine provide a great protection to clinical M. hyopneumoniae and PCV2 infection.